Joshua C. Doloff @DoloffLab
Doloff Lab: Immunoengineering & Regen Med @TTECJHU | Ugrad @Penn @PennBioeng | PhD @BU_Tweets | Postdoc @MIT | Assoc. Prof. @JohnsHopkins @JHUBME DEI FLI YNWA! bme.jhu.edu/dolofflab/ Baltimore, MD Joined October 2018-
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@JudeM_Phillip @DrWoappi @NatureComms @JHUBME @INBT_JHU @KKLabJHU Congrats Jude and team!
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Joshua C. Doloff retweeted
T cell immunity declines with thymic atrophy, but thymic cell grafts rescue T cell function go.nature.com/3Jp6B72 rdcu.be/4C6R4B1ZJaWa
Joshua C. Doloff retweeted
The @JohnsHopkins BME undergraduate program is once again ranked No. 1 in the nation by @usnews. Students dive into hands-on research from day one, helping drive innovation in human health. Read more: bme.jhu.edu/news-events/ne…
Joshua C. Doloff retweeted
Proud of our @nyulangone Dean (and prior @Perlmutter_CC Director) Alec Kimmelman for his @Nature paper today: Hepatocytes promote liver metastasis of #PancreaticCancer by providing serine nature.com/articles/s4158… With @BarDafna @RichPossemato @KoelinaG @nyugrossman
Joshua C. Doloff retweeted
Cancer patients waste away partly because their own fat starts burning itself. The signal that starts it is not a cytokine. It is iron. Could this insight lead to a drug to prevent cachexia in cancer patients? doi.org/10.1038/s43018…
Joshua C. Doloff retweeted
An experimental blood test detected 87% of early-stage pancreatic ductal cancers in an international study.
Joshua C. Doloff retweeted
Plasticity of the infant immune system during the perinatal period dlvr.it/TVXqvS
Joshua C. Doloff retweeted
Macrophages eating living cells...NATURE paper ! nature.com/articles/s4158…
Joshua C. Doloff retweeted
Pain producing neurons around #cancer generate immune suppressive molecules... The neuroimmunology of cancer is crazy...and its an area that is highly overlooked.... nature.com/articles/s4158…
Joshua C. Doloff retweeted
We’re hiring! Join the Hickey Lab at Duke as a full-time Research Assistant developing reproducible agent-based models of human tissues. We seek experience in Python, computational modeling, and biology. 1–2 years, Durham, NC. Apply/share: forms.gle/Abfbwb4B8a8Wyc…
Joshua C. Doloff retweeted
Excited to share our new review in @CellCellPress. We propose fibrosis is a reversible state encoded in chromatin circuits shaped by immune-stromal crosstalk, and that rewiring this logic may offer durable therapeutic paths. @GladstoneInst authors.elsevier.com/sd/article/S00…
Joshua C. Doloff retweeted
Engineering our immune cells has successfully treated many types of cancer and even led to cure of some autoimmune diseases. But the engineering of cells was done outside the body, is highly complex, takes 3 to 6 weeks, and is not scalable. But now there are many in vivo (inside the body) Phase 1 clinical trials reading out soon. Watch this space. nature.com/articles/d4157…
Joshua C. Doloff retweeted
The longest lived people among us, called "supercentenarians," have an abundance of cancer-killing immune cells, study finds. Learn more in Cell Reports: cell.com/cell-reports/f… Kosuke Hashimoto, Nobuyoshi Hirose, Piero Carninci, Yasumichi Arai, & colleagues @CellReports
Joshua C. Doloff retweeted
Using single-cell immune profiling, scientists from the University of Osaka analyzed T cells from #supercentenarians and found that cytotoxic T lymphocytes begin to expand around the age of 100, characterized by sequential CD27/CD28 loss without exhaustion. bit.ly/4y8im5t 📖: @CellReports
Joshua C. Doloff retweeted
Huge faculty recruitment effort at the University of Chicago -- a division-wide, open-rank search looking to hire about 20 faculty across 5 research areas in biology. Come be our colleague! Full announcement: uchicago.app.box.com/s/ckih9zv3rjlj…
@TheFentonLab @UNC @UNCPharmacy @DPMP_UNC Congrats Owen!
Joshua C. Doloff retweeted
#Bcells favor different #memory fates in response to barrier tissue infections, forming plasma cells in the gut and memory B cells in the lungs in mice. Learn more in Science #Immunology: scim.ag/4wae4tK
Happy to share a recent publication with our collaborators at Wilmer on crystalline drug delivery to the eye to treat wet age-related macular degeneration @JCRnEDITORS! sciencedirect.com/science/articl… & Recent press release: bme.jhu.edu/news-events/ne… @JHUBME @TTECJHU @HopkinsMedicine
@WJGreenleaf @LuoZhifei You guys already working on gen2 called PIP-skweq?
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