Horvath Lab @HorvathLab
The Horvath Lab is a research group at @Cambridge_Uni with a focus on mitochondrial diseases and inherited neuropathies. www-neurosciences.medschl.cam.ac.uk/horvathlab/ Cambridge Joined February 2020-
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Congratulations @LakatosLab and team! Fantastic paper!
Connectoids: Our latest Human Brain-Spinal Cord-Muscle Organoid-Slice Connectoid model: cell.com/cell-reports/f… @Cambridge_Uni @The_MRC @SCICambridge @BrainRepair_VGB @SpinalResearch @organoidscience @OrganoidSphero1 @OrganoidAtlas
Congratulations @mitocollier and @mitodynamics . What a fascinating story on mtDNA release and pyroptosis-must read!
Connectoids: Our latest Human Brain-Spinal Cord-Muscle Organoid-Slice Connectoid model: cell.com/cell-reports/f… @Cambridge_Uni @The_MRC @SCICambridge @BrainRepair_VGB @SpinalResearch @organoidscience @OrganoidSphero1 @OrganoidAtlas
🚨🚨Our new paper is out! We discuss the potential of nucleoside supplementation as a treatment for RRM2B. Many thanks to all that contributed to this research!
🧬 New paper! We nudge the science forward surrounding deoxynucleoside supplementation & mitochondrial DNA depletion syndromes (MDDS). We show, for the first time in vivo, that deoxynucleoside supplementation can mitigate effects of RRM2B mutations.🔗 academic.oup.com/hmg/advance-ar…
📢We are hiring a #research coordinator to work on all things MitoCAMB and the @lifearc1 centre to treat #mito diseases. Rolling recruitment throughout Jan. Apply here: 👉 jobs.cam.ac.uk/job/48491/ 👈 @Jellevda @HorvathLab @4Lilyfoundation @RobPitceathly @taylorlabncl @MRC_MBU
A 2023 Review in Science Translational Medicine looks at the complex connections between astrocytes and other types of cells in the nervous system, including neurons, oligodendrocytes, and microglia. Learn more: bit.ly/4esssnw #ScienceMagArchives
🎉We are delighted to share exciting news from the uOttawa Brain and Mind Research Institute (@uOttawaBMRI) that Dr Hanns Lochmüller and Dr @MireilleKhacho have been appointed as the new leaders of the Neuromuscular Health research hub!
We are hiring! Exciting Research Coordinator job opportunity working with the #MitoCAMB team as part of the national @lifearc1 #raredisease centre: jobs.cam.ac.uk/job/48491/ Please RT! 📢 @HorvathLab @Jellevda @MitoResearch @4Lilyfoundation @mitojobs @Cambridge_Uni @CamNeuro
👨🔬We've just invested nearly £80K into a new project that could potentially alleviate symptoms for patients diagnosed with MNGIE. 👩🔬 If you'd like to read more about their research click the link below for more information. @cam_mito ow.ly/ZrRA50TvYSn
Preparations are already underway! @HorvathLab
We’re funding research on a potential new treatment for #MitochondrialMyopathy! 💊 Prof Rita Horvath’s team at @Cambridge_Uni is exploring a dietary supplement as an option to manage the condition. 🌿 Read more this #MitochondrialAwarenessWeek: loom.ly/6DKWrQ8
During #mito disease awareness week the whole MitoCAMB team has come together to share knowledge, experience & ideas at our away day. Lots of fun, but also a chance to build relationships & facilitate even better research for the future! @Jellevda @HorvathLab @MRC_MBU @NellNie
💚IT'S HERE!!!!!💚 💚World Mitochondrial Disease Week Has Begun!!!💚 👀Keep your eyes peeled for some fabulous posts coming up this week!👀 🧑🤝🧑Together we can continue to raise awareness around mitochondrial disease!🧑🤝🧑
Many thanks @MDUK_News for funding our project. Very excited about the future research into amino acid supplementation of mt-aars patients More details below:👇🏻 bbc.co.uk/news/articles/…
Exciting Clinical Research Associate job opportunity working with #mitoCAMB team on #mito research as part of the @lifearc1 #raredisease centre: jobs.cam.ac.uk/job/48056/ Please RT! 📢 @EastNeurology @HorvathLab @Jellevda @MYTiet @UCLIoN @UCL_QS_CNMD @taylorlabncl @MitoResearch
Astrocytes exert both gain and loss of function pathologies in ALS, providing a dilemma in therapeutics. Prompted by our recent paper in @braincomms, we revisited our earlier works in @CommsBio + @NatureNeuro @NaturePortfolio @NatureComms at go.nature.com/4fTJvko for AC lovers.
Szebényi et al. report that the knockdown of pleckstrin homology-like domain family A-member 3 diminishes reactive oxygen species release by human spinal astrocytes harbouring the superoxide-dismutase-1 #ALS mutation. @LakatosLab edin.ac/3WBD64r
We were delighted to work with the @4Lilyfoundation & their expert patient input committee to develop a leaflet for patients diagnosed with #mito disease. It provides basic info and signposting to more resources locally and across the UK! @Jellevda @HorvathLab @MitoResearch
Calling #mito #Researchers! Looking to include the patient voice in your research, look no further! Our Expert Patient Input Committee made up of #mito patients, their families & carers keen to help shape research, clinical care & treatments. Email:[email protected]
🚨🚨Excellent opportunity to join our clinical research team!
📢We are hiring! A Clinical Research Manager to join the friendly and enthusiastic MitoCAMB team! A really interesting and diverse job working on world-class research in #mito disease. #joinus jobs.cam.ac.uk/job/47191/ @Jellevda @HorvathLab @MRC_MBU @CamNeuro @camraredisease
📢We are hiring! A Clinical Research Manager to join the friendly and enthusiastic MitoCAMB team! A really interesting and diverse job working on world-class research in #mito disease. #joinus jobs.cam.ac.uk/job/47191/ @Jellevda @HorvathLab @MRC_MBU @CamNeuro @camraredisease
Congrats to @chrismutti1 on publishing his PhD research on mitoribosome assembly! This builds upon @LindseyVanHaute's work on the methyltransferase METTL15, revealing that its catalytic activity is not essential for mtSSU biogenesis. tandfonline.com/doi/full/10.10… @MBU_postdocs @MRC_MBU
We are delighted to announce that Hanns is this year’s winner of the Researcher of the Year award conferred by @uOttawaMed and @OttawaHospital.🥳Congratulations Hanns, your team is very proud of you! 🏆Read more about the award: lochmullerlab.org/?p=349627
We’re VERY pleased to be working with @4Lilyfoundation @UCL_QS_CNMD @taylorlabncl & @MDUK_News on the @lifearc1 Centre for #Rare #mito diseases! We hope this will have a huge impact on #Raredisease research and #mito patients. @RobPitceathly @MikeHanna18 @HorvathLab @Jellevda
We're launching 4 Translational Centres for Rare Diseases! 1️⃣ Centre for Rare Respiratory Diseases 2️⃣ LifeArc @Kidney_Research Centre for Rare Kidney Diseases 3️⃣ Centre for Rare Mitochondrial Diseases 4️⃣ Centre for Acceleration of Rare Disease Trials @MDUK_News @4Lilyfoundation
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