Muir Lab @Muir_Lab
(Extra)Cellular Cancer Biology @UChicagoCCB. themuirlab.org Chicago, IL Joined January 2014-
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Muir Lab retweeted
We at @PanCAN were pleased to see the release of the updated @NCCN Pancreatic Adenocarcinoma Guidelines.
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Muir Lab retweeted
I’m excited to share new work out of the lab at @nyulangone led by @KenjiFujihara! We took a first principles approach to evaluating #ferroptosis induction for cancer therapy via targeting the SLC7A11-glutathione-GPX4 axis. biorxiv.org/content/10.648…
Muir Lab retweeted
Announcing our 2026 CMH Postdoctoral Rising Stars Symposium on Wednesday, September 2! To apply for this opportunity, scan the QR codes on the flyer or visit our track links: Metabolism (shorturl.at/rjV1N) and Health Behaviors (shorturl.at/ayq8p). Help spread the word
Muir Lab retweeted
Thrilled to share our work in press @jclinicalinvest where we modernize a hallmark experiment originally performed by the Coris by performing intra-operative metabolite sampling in lung cancer patients jci.org/articles/view/…
Muir Lab retweeted
Excited to announce that registration is officially open for #METPHYS2026! All meeting details can be found here: sablesys.com/metphys-the-me…
Muir Lab retweeted
Out today 🙌 new work from the lab in which we show that p53-driven senescence enables phospholipid headgroup recycling to help sustain the increased synthesis of membrane phospholipids of senescent cells nature.com/articles/s4155…
Muir Lab retweeted
I love this concept. Although framed around #aging research, I think it can extend beyond that. We can use a synthetic approach, to study basic principles of cell biology and potentially mitigate human disease by engineering unique bacterial enzymes. science.org/doi/10.1126/sc…
Muir Lab retweeted
New! Online now: A metabolic atlas of mouse aging dlvr.it/TPSYYS
Muir Lab retweeted
New @CR_AACR study by @Cosimo_Commisso The Aging Microenvironment is a Determinant of Immune Exclusion and Metastatic Fate in #PancreaticCancer aacrjournals.org/cancerres/arti…
Muir Lab retweeted
🗽Save the date! March 24, 2026 Cancer Metabolism and Signaling Symposium @NYASciences co-organized by @LyssiotisLab @RichPossemato Speakers: @lab_manning @bensahralab @MarcusDGon @airdlab @KanarekNaama @JaviGBermudez @SantoshVardhana Josh R, Erika P +short talks from abstracts!
Muir Lab retweeted
Happy to share our new review (featuring Joe Longo and McLane Watson) on how T cells use nutrient allocation to optimize immune responses. @VAIMetabolism @VAInstitute sciencedirect.com/science/articl…
Muir Lab retweeted
Big news from the #Glytsoulab today!✍️Our research on drug resistance in leukemia is published in @ScienceAdvances. Targeting OPA1 can help overcome therapy resistance in AML, including the most challenging cases. 📖 science.org/doi/10.1126/sc…
@glytsou @ScienceAdvances Congrats! Very cool!
Muir Lab retweeted
Our new work in @Cell_Metabolism by @ArtemAKhan describes three new SLC transporters, including SLC25A45, a mitochondrial transporter for methylated amino acids that is essential for carnitine synthesis and fasting adaptation. @RockefellerUniv cell.com/cell-metabolis…
Muir Lab retweeted
This cool @ScienceMagazine paper links extracellular pH milieu (acidosis) to an intra-cellular oncogenic signaling pathway & metabolic rewiring in #PancreaticCancer. Acidosis orchestrates adaptations of energy metabolism in tumors science.org/doi/10.1126/sc…
Muir Lab retweeted
Wonderful talk by @DebVendramini @HenryFordHealth on adaptation & plasticity of the stromal and #CancerAssociatedFibroblasts microenvironment in driving immune suppression in #PDAC #AACRPan25 @RAFrancescone
Muir Lab retweeted
Location, location, location! Now out in @NatureCancer, the final version of our study showing how a tumor's anatomic site can impact the function of driver gene mutations, using SMAD4 inactivation in pancreatic cancer as a clin. relevant example: nature.com/articles/s4301…. (1/3)
@OlzmannLab @Aiims1742 @ColinSh21573670 Thanks James!
Super excited to share our new preprint from @ColinSh21573670 on how the tumor microenvironment causes drug resistance in pancreatic cancer: biorxiv.org/content/10.110…
Muir Lab retweeted
Excited to share the lab’s first pre-print! Here we investigate how #nutrient availability regulates #ECM composition, mechanical properties and biological activity. biorxiv.org/content/10.110…
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