The Science of Parkinson's @ScienceofPD
Personal account of the Director of Research at @CureParkinsonsT - All views my own - Kiwi - Kia kaha - 侘寂 scienceofparkinsons.com London, England Joined January 2016-
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Movement disorders neurology remains an act of watching. @janealty1 & @vertigologist explore computer vision for the detection of deterioration in #Parkinsons. But if "no effective intervention or care response is available, have we actually helped"? nature.com/articles/s4153…
Mission Therapeutics @MISSIONTherapeu announces dosing of first #Parkinsons patient in the Phase 1b study of their USP30 inhibitor MTX325. The study is taking place in UK, Europe & Australia. Readout is anticipated in late 2027 missiontherapeutics.com/mission-therap…
Curiously, both of these ARBs are traditionally considered non-CNS penetrant "both produce insurmountable, slowly reversible AT1 blockade with prolonged receptor residence times, whereas losartan binds in a surmountable, rapidly dissociating manner"
Using large-scale hospital electronic health records of the University of California health system (n=890K hypertensive patients), researchers report Angiotensin receptor blockers irbesartan & olmesartan were associated with lower incident #Parkinsons risk onlinelibrary.wiley.com/doi/10.1111/fc…
XellSmart presented 6 months post-transplant data for their Phase I trial of their off-the-shelf #Parkinsons cell therapy XS411, & announces successfully completion of enrollment for the Phase 2 trial of XS411 prnewswire.com/news-releases/…
Something researchers to explore: The GBA1 Canada initiative (G-can) - a pre-competitive, collaborative, open-science platform accelerating research & treatment development for GBA1-related #Parkinsons journals.sagepub.com/doi/10.1177/18…
New research suggests dietary patterns/habits in isolated REM sleep behavior disorder is associated with gut microbiome dysbiosis & predicts neurodegenerative progression, highlighting diet–microbiome interactions as modifiable factors …mentdisorders.onlinelibrary.wiley.com/doi/10.1002/md…
Researchers virtually screen of 9.4k compounds (2.6k FDA-approved drugs, 6.7k African natural products) against the ATP-binding pocket of LRRK2-G2019S, & identify Rimonabant, Gallagic acid, Acalabrutinib, & Atovaquone as repurposable candidates nature.com/articles/s4159…
Researchers report a case of #Parkinsons caused by a de novo SNCA triplication with longitudinally evaluated gene expression in whole blood & platelets at 2 disease stages: early PD (age 41) & Parkinson's disease dementia (age 44) …mentdisorders.onlinelibrary.wiley.com/doi/10.1002/md…
New research from the GP2 team finds that the GCH1 p.Ser80Asn variant is a rare, East Asian-enriched risk variant for #Parkinsons …mentdisorders.onlinelibrary.wiley.com/doi/10.1002/md…
Another week, another paper for @GeorgeTofaris & colleagues This week, they report the epitope accessibility & topology of extracellular vesicle-associated α-synuclein proteoforms, rather than their abundance alone, discriminate synucleinopathy subtypes academic.oup.com/brain/advance-…
New review explores resilience & vulnerability in the midbrain dopamine system during aging; "Elucidating these neuroadaptive mechanisms could offer a path toward preserving dopamine neuron function across the lifespan" & possibly preventing neurodegen. cell.com/trends/neurosc…
New editorial raises concerns about Vitamin B6 levels in #Parkinsons, & the need for monitoring them …mentdisorders.onlinelibrary.wiley.com/doi/10.1002/md…
Towards a better definition of patient-centered therapeutic strategy of #Parkinsons: A new opinion paper proposes "pragmatic, consensus-based principles for fully individualized, preference-sensitive pharmacological care across the patient journey" link.springer.com/article/10.100…
Perspectives on ionizing radiation & #Parkinsons "Emerging evidence from epidemiological studies in humans exposed to ionizing radiation (IR) suggests a positive association between IR & a specific neurological disorder, Parkinson’s" nature.com/articles/s4153…
Results in the Parkinson's Precision Medicine Initiative (PPMI) indicate that a-synuclein-seed amplification assay testing results are highly consistent over time …mentdisorders.onlinelibrary.wiley.com/doi/10.1002/md…
"Artistic expression offers unique insights beyond structured assessments, fostering empathetic clinician–patient communication, & supporting a more holistic, person-centered approach to PD care". State of the “Art” in Freezing of Gait from @basbloem et al onlinelibrary.wiley.com/doi/10.1111/ej…
The 2026 therapeutic development pipeline for Frontotemporal lobar degeneration has been published alz-journals.onlinelibrary.wiley.com/doi/10.1002/tr…
"Intranigral AAV8-Irisin delivery did not produce statistically significant improvement in either motor performance or dopaminergic neuron survival" in a preclinical #Parkinsons (AAV9-A53T mouse) model. Peripheral AAV8-Irisin had no impact as well frontiersin.org/journals/aging…
Press summary associated with this research: medicalxpress.com/news/2026-10-d…
Researchers present a second-generation “hypoxia in a pill” (combining a hemoglobin affinity enhancer to limit oxygen delivery with a HIF-2α inhibitor) intervention that rescues neurodegen. phenotypes across different mouse models, including #Parkinsons pnas.org/doi/10.1073/pn…
Michael Okun @MichaelOkun
40K Followers 671 Following Neurologist, Author, The Parkinson’s Plan, Medical Advisor Parkinson’s Foundation, Distinguished Professor UF Fixel Institute
Alberto J Espay @AlbertoEspay
10K Followers 601 Following #Neurology professor @uofcincy, advocate of precision medicine in neurodegeneration, author #BrainFables. More active on LinkedIn.
MDS @movedisorder
17K Followers 313 Following MDS is a professional society of clinicians and other healthcare professionals interested in movement disorders. #movedisorder @MDJ_Journal | @MDCP_Journal
Jonny Acheson @jonny_acheson
7K Followers 1K Following Husband, Dad, Emergency Medicine doctor, Artist. Parkinson's 2016. Thankful for grace. Work with @ParkinsonsEN. Author of ‘When Your Neurons Dance' Views my own
Alfonso Fasano @DrAlfonsoFasano
7K Followers 2K Following Toronto Western Hospital | Krembil Brain Institute | Professor of Neurology, University of Toronto Professor of Neurology, Humanitas University, Milan
Richelle Flanagan �... @RichelleFlan
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Kailash Bhatia, @kailashbhatia
7K Followers 2K Following Professor of Clinical Neurology, Queen Square, UCL; founding editor MDCP; opinions my own
Andrew Lees @ajlees
10K Followers 986 Following Professor of Neurology at UC London Author of Ray Kennedy biography, The Hurricane Port, Mentored by a Madman, Brazil that Never Was and Brainspotting.
Gavin Mogan @purposeful_pd
3K Followers 702 Following Personal Trainer to Parkinson’s warriors - move to your groove. Lawn-care for the soul - mow with the flow. Ball.
Bas Bloem @basbloem
14K Followers 915 Following Professor Neurology @radboudumc | Director Center of Expertise for #Parkinson & Movement Disorders | Board @ParkinsonNet | Editor in Chief @journal_PD
@tapehead81 @tapehead81
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Cure Parkinson's @CureParkinsonsT
22K Followers 2K Following We’re here for the cure. Cure Parkinson’s is working with urgency to find new treatments to slow, stop and reverse Parkinson’s.
Parkinson's UK @ParkinsonsUK
71K Followers 6K Following We’re Parkinson’s UK, the charity that’s here to support every Parkinson’s journey. Every step of the way.
K Ray Chaudhuri @KRayChaudhuri1
3K Followers 677 Following Director Parkinson Centre of Excellence, Professor of Neurology, Movement Disorders at King’s College London. Research Director and EDI lead ARC.
Patrik Brundin MD PhD @BrundinPatrik
4K Followers 872 Following MD PhD, Therapeutic Area Leader for Movement disorders at @Roche Expert on #Parkinson and #Huntington disease. Views expressed here are my own.
Matt Eagles ⚒️ @MattEagles
7K Followers 8K Following - all views my own ⚒lifelong Hammers fan and lived with Parkinson's for 50 years #posivityactivist #patientadvocate
Indu Subramanian @DrISubramanian
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Parkinson's Humor �... @YumaBev
4K Followers 2K Following Parkinsons symptoms since the 80's, finally diagnosed in '07, bilateral STN DBS in '12. Funny stories & helpful tips about life. Come laugh with me 🤣
Oscar Gershanik @GershanikOscar
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charles beardall @BeardallCharles
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Sun @Suno7ti
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RAF @RAF1893
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PastePlate-AI @pasteplate_ai
0 Followers 14 Following Health coaching app Your AI as nutrition coach: ChatGPT, Claude, Gemini Reports on your phone · no cloud · 30 plants/week ⬇️ Try free for 7 days
durga nandan @nandan_dur94846
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Hicham lamri @lamrihicham
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A.u.r.a.K.a.i - React... @aurakairegen
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Human Notes @Humannoteshn
2 Followers 29 Following Every interface changes the cost of a verb. I have Parkinson’s. I live with interfaces. I observe what changes. Human Notes makes verbs visible.
Shantanu @ShantanuReal
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Patrick with Parkinso... @patrickwithpd
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Glen Greeley @glgreeley
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Olawale Agbomeji @physiowale
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Marco Galvrz @MGalvrz94014
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Chini @Chiniuzala
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Gabriela @GabrGueza
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Jack Gommers @JackGommer2g
361 Followers 4K Following Volksgezondheid en voedselveiligheid👉Mijn eerder account Jack Gommers is gehackt.‼️‼️ @GommersJack
Ozoswita Roy @RoyOzoswita
20 Followers 573 Following Cognitive Science Researcher @ IIIT-Hyd Memory Neuroscience
Jana @Jana83244101
185 Followers 3K Following
Rosie Fuest @RosieFuest
73 Followers 143 Following
Yu-ichiro Nakajima @nyuichiro97
889 Followers 734 Following Biologist, studying tissue homeostasis, environmental responses, cellular plasticity 🪰🪼 Like sports & cooking. 恒常性, 環境応答, 細胞可塑性の研究＠東大薬学
Randell LaRock @randelllarock
6 Followers 224 Following Freelance Writer 518-744-6357 [email protected] Freelance Writer!
Amin Atashgaran @mnatashgaran
41 Followers 490 Following
Sheetal Bhandari Jaju @SheetalSJaju
1 Followers 93 Following
Emmanuel H During, MD @DuringMd
181 Followers 177 Following Neuro-Sleep and RBD Expert, Researcher in Prodromal Parkinson's Disease, Building the https://t.co/jnUZfJETeK
Jonathan Rezek @KuriouserGeorge
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Dana Egert @egert_d
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Kimberley Miller @CoopateBirwin
1 Followers 24 Following
Debraj Koiri @Debrajkoiri
71 Followers 659 Following Doctoral student || National institute of science education and research,India
wayne lee @youpiquee
4 Followers 145 Following
Eduardo Calçada @ForadaCasca
3 Followers 27 Following
pawsitive nic @NickyAnicola4
33 Followers 187 Following Don’t ask me the question if you don’t want to know the truth!
Mohammad Alomary @MohammadAl17729
24 Followers 2K Following
d dolias @DDolias
5 Followers 90 Following
Moeen Zafar @moeenzafar63
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Janelle @Janelle_M08
1 Followers 55 Following
toxicmoldavenger @toxicmoldaveng1
2 Followers 927 Following American in Europe. Mom, Wife, Spiritual. ✨🌙💫⭐️Olive Oil Enjoyer. Natural Health Enthusiast.
Anubhab Biswas @AnubhabBW
2 Followers 5 Following সুখি, বিষ্ময়কর এবং হতাশ! ANRF Project Associate-I; CSIR-CCMB 👨🏻🎓IISERite; BS-MS Biological Sciences; IISER Berhampur 📍HYD
kickinelle @kickinelle
179 Followers 3K Following currently collecting jerseys, random sunsets 🌅 and way too many match predictions with friends
Daly marithe Clara @Dalymarithcov6
383 Followers 7K Following
Michael Okun @MichaelOkun
40K Followers 671 Following Neurologist, Author, The Parkinson’s Plan, Medical Advisor Parkinson’s Foundation, Distinguished Professor UF Fixel Institute
Alberto J Espay @AlbertoEspay
10K Followers 601 Following #Neurology professor @uofcincy, advocate of precision medicine in neurodegeneration, author #BrainFables. More active on LinkedIn.
MDS @movedisorder
17K Followers 313 Following MDS is a professional society of clinicians and other healthcare professionals interested in movement disorders. #movedisorder @MDJ_Journal | @MDCP_Journal
Alfonso Fasano @DrAlfonsoFasano
7K Followers 2K Following Toronto Western Hospital | Krembil Brain Institute | Professor of Neurology, University of Toronto Professor of Neurology, Humanitas University, Milan
Andrew Lees @ajlees
10K Followers 986 Following Professor of Neurology at UC London Author of Ray Kennedy biography, The Hurricane Port, Mentored by a Madman, Brazil that Never Was and Brainspotting.
Brain @Brain1878
76K Followers 166 Following Brain: A Journal of Neurology. Publishing leading studies in neurological science since 1878.
Bas Bloem @basbloem
14K Followers 915 Following Professor Neurology @radboudumc | Director Center of Expertise for #Parkinson & Movement Disorders | Board @ParkinsonNet | Editor in Chief @journal_PD
@tapehead81 @tapehead81
6K Followers 6K Following film maker. songwriting. piano. shed life. #parkinsons since 2011. #DBS 2019.
michaeljfox.org @MichaelJFoxOrg
96K Followers 2K Following The Michael J. Fox Foundation is dedicated to finding better treatments and, ultimately, a cure for Parkinson’s disease. Social Info: https://t.co/jN2BqHCali
Cure Parkinson's @CureParkinsonsT
22K Followers 2K Following We’re here for the cure. Cure Parkinson’s is working with urgency to find new treatments to slow, stop and reverse Parkinson’s.
Parkinson's UK @ParkinsonsUK
71K Followers 6K Following We’re Parkinson’s UK, the charity that’s here to support every Parkinson’s journey. Every step of the way.
K Ray Chaudhuri @KRayChaudhuri1
3K Followers 677 Following Director Parkinson Centre of Excellence, Professor of Neurology, Movement Disorders at King’s College London. Research Director and EDI lead ARC.
Patrik Brundin MD PhD @BrundinPatrik
4K Followers 872 Following MD PhD, Therapeutic Area Leader for Movement disorders at @Roche Expert on #Parkinson and #Huntington disease. Views expressed here are my own.
Neurology Journal @GreenJournal
100K Followers 1K Following Neurology is the most widely read and highly cited peer-reviewed neurology journal. It is the medical journal for the American Academy of Neurology.
Andreas Horn @andreashorn_
10K Followers 2K Following Former account – Now at @andreashorn.org on bluesky. https://t.co/pohTcnIvXN
Parkinson's Europe �... @ParkinsonsEU
8K Followers 2K Following 🌷The leading voice for #Parkinson's in Europe since 1992 🌷Supporting the 1.2m Europeans with #Parkinsons and their families 🌷Founder of #WorldParkinsonsDay
Abhimanyu Mahajan @AMahajanMD
6K Followers 2K Following Movement disorders neurologist and Associate Professor at the University of Cincinnati. Views are my own and never medical advice.
Ziv Gan-Or @ZivGanOr
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1K Followers 2K Following Dad, husband, Hearts fan, occasional writer and patient advocate. Likes /RT are not endorsements. https://t.co/9znpM7geSL
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ELRIG @ELRIG_SCIENCE
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The International RBD... @IRBD_StudyGroup
66 Followers 72 Following The official account of the Internaitonal RBD Study Group
Movers & Shakers: a p... @moversand6
3K Followers 86 Following Movers and Shakers, a Parkinson’s podcast with Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Nick Mostyn and Jeremy Paxman
HOW THINGS WORK @HowThingsWork_
2.4M Followers 7K Following The Official How Things Work page including Tech, Finance, AI & loads more. Also all the best News & Viral content from around the globe.
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West Laboratory @DukeWestLab
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David Standaert MD, P... @DavidStandaert
550 Followers 211 Following Chair, Department of Neurology, UAB Heersink School of Medicine. @uab_neurology Tweets=mine
Björn Schumacher @schumacherbj
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UK Parkinson’s Dise... @UK_PD_CSG
478 Followers 525 Following Developing & supporting #Parkinsons clinical research across the UK & increasing research opportunities for people with Parkinson's. Funded by @CureParkinsonsT.
The East London Parki... @EastLondonPD
146 Followers 85 Following Parkinson's phenotype, determinants & biomarkers in diverse pop/n. @preventiveneur1 unit. Team @predictPD @TahrinaH @Alex_Zirra @f_huxford @Kamalesh_Dey + more.
Dr. Glaucomflecken @DGlaucomflecken
683K Followers 434 Following Ophthalmologist. Comedian. Speaker. Tiktok. Contact: [email protected] Bluesky: https://t.co/XXBQPt82Qg
NoSilverBullet4PD @NSB4PD
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mito911 @mito911_
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LRRK2 Central @LRRK2_central
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John D Carroll @JohnCendpts
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EJS ACT-PD @EJS_ACT_PD
243 Followers 164 Following Designing the first MAMS trial for patients with Parkinson’s disease, funded by the Edmond J. Safra Foundation led by @foltynie @UCL & @CamilleBCarroll @PlymUni
Deep Brain Stimulator @DeepStimulator
65 Followers 9 Following Deep tweets from deep inside a human brain.
John Burn-Murdoch @jburnmurdoch
476K Followers 6K Following Columnist and chief data reporter @FinancialTimes | Stories, stats & scatterplots | Senior fellow @LSEdataScience | [email protected]
HDBuzz @HDBuzzFeed
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laurent roybon @LRoybon
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ARCHIVED - NASA's Per... @NASAPersevere
2.9M Followers 39 Following This account has been archived. Follow @NASAMars to get the latest updates on the Perseverance rover’s mission.
Deepak @iammdeepak
80 Followers 679 Following Humanist. Cricket is the only religion and Tendulkar and Warnie the only gods. Aspiring vegan Views expressed are mine. Retweets/Likes are not endorsements
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138K Followers 1K Following Fighting for social justice. Co-Executive Director, @BeAHero. Husband to @rachael_scar, Abba to Carl & Willow. Paralyzed by ALS. Author: Eyes to the Wind.
PD Avengers @PdAvengers
3K Followers 544 Following We are a global alliance of people w/ Parkinson's, our partners & friends aligned to add urgency to the cause of ending PD through wellness, advocacy & research
Aligning Science Acro... @ASAP_Research
2K Followers 339 Following Global initiative accelerating #ParkinsonDisease research. Join us on LinkedIn and Bluesky.
Will Cook @WillCookCPT
163 Followers 55 Following Does a lot of work for charity; does like to talk about it. Ex-trustee, ex-CEO now Chair of Development Board of @CureParkinsonsT
David Breen @breenneurology
636 Followers 995 Following Neurologist. Movement disorders specialist. Researcher. Dad of three. @AnneRowlClinic @EdinUniBrainSci @EdinUniUsher
Oded Rechavi @OdedRechavi
146K Followers 1K Following Transgenerational inheritance, q.e.d: @qedscience https://t.co/tKNk6qiSlZ TED: https://t.co/rcOm9TSTf5 Huberman Lab Podcast: https://t.co/xZTNlx9nbi
PDgenetics.org @pdgenetics
849 Followers 337 Following International Parkinson Disease Genomics Consortium (IPDGC)
LARGE-PD @LARGE_PD
436 Followers 252 Following We are the Latin American Research consortium on the GEnetics of Parkinson's Disease.
Younger Parkinson’s... @ParkinsonYoung
392 Followers 78 Following "Parkinson’s isn’t a condition that only older people get, as I found out when I was diagnosed at the age of 39..." Sarah Webb (@slwcowen) #parkinsons #yopd
Beckham Lab @NS3protease
190 Followers 107 Following An infectious disease lab that studies emerging RNA viruses and neuroimmunology at UTSouthwestern Medical Center.
Trevor Bedford @trvrb
399K Followers 750 Following Scientist @fredhutch, studying viruses, evolution and immunity. Collection of #COVID19 threads here: https://t.co/Yc4fun5rcp
Parkinson's Foundatio... @PFResearchTeam
1K Followers 151 Following @ParkinsonDotOrg knows that a research breakthrough can happen at any time & believes in educating our PD community with the latest research updatesTrends for United States
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